Dr Paul Mainwaring


Dr Paul N Mainwaring MBBS (Syd. 1989) FRACP (1992) MD (Lond. 2002)

As senior practising medical oncologist, with emphasis on research and application of new technologies and a holistic approach to deliver the best available personalised care to patients and their carers.

In 2019, Paul transitioned across to working with the XING Technologies teams to deliver their innovations.

Paul’s initial Medical Oncology training was undertaken in Sydney at Royal Prince Alfred and Royal North Shore hospitals before moving to the Royal Marsden, London – initially as Gynaecologic Oncology Research Fellow (under Prof. Martin Gore) then as Breast Cancer Research Fellow (under Prof. Ian Smith).

Paul gained experience at the Institute of Cancer Research undertaking an MD in cell death in the laboratory of Prof. Mitch Dowsett and thereafter gained his UK qualifications, thereafter consulting to Guy’s, King’s and St Thomas’ NHS Trusts and conducting rooms at the London Bridge and Harley St Oncology Clinics.

In 2002, Paul returned to Australia as Director of Medical Oncology, Mater Adult Hospital. He was responsible for establishing a solid tumour oncology research program that collaborated with basic laboratory researchers (Prof. Derek Hart) utilising the latest genetic and pharmacology technologies applied to phase I (first in man) new cancer drug development and dendritic-cell therapy.

In 2008, Paul joined ICON Cancer Care and continued his clinical research as well as clinical care activities, leading to multiple first in Australia phase II/III trials. As a result of his clinical research, Paul has published national, international studies incorporating phase I (first-in-man), phase II (proof of safety/efficacy), phase III (randomised new therapy vs. standard) and past-marketing (phase IV) trials sponsored by philanthropy, co-operative group as well as the pharmaceutical industry.

He has published extensively in the New England of Medicine, Lancet, Lancet Oncology, Journal of Clinical Oncology amongst others.

In 2013, XING Technologies was co-founded with Prof. Mathias (Matt) Trau to commercialise technologies created in his laboratory.


  • M.D. University of London F.R.A.C.P.


  • M.B.B.S. University of Sydney


Career Appointments

  • CANOSSA Private Hospital July 2017 to present
  • iCON Cancer Care Jul 2010 to July 2017
  • Medical Oncologist
  • Senior Principal Clinical Research Investigator
  • Mater Medical Research Institute 2007 to 2010
  • Senior Principal Clinical Research Investigator
  • Haematology & Oncology Clinics of Australasia 2004 to 2007
  • Visiting Consultant Medical Oncologist
  • Mater Health Services 2003 to 2004
  • Director, Medical Oncology

Career Highlights

1999-2002     Consultant, Guy’s, King’s & St. Thomas Cancer Centre, London

1995-1998     Medical oncology training, Royal Marsden NHS Trust, London

1994               Medical oncology training, Royal North Shore Hospital, Sydney

1992-1994     Medical oncology training, Royal Prince Alfred Hospital, Sydney