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ABOUT XING Cancer Tests

We are an Australian-owned and operated cancer pathology lab that uses genetic sequencing to inform doctors and patients about precision cancer treatment options.

Precision medicine offers cancer patients therapy options that are targeted specifically to their cancer. XING Genomic Services offers a range of cancer genetic tests for both newly diagnosed cancer patients and patients dealing with a recurrence of their disease.
The results analysed in our lab will determine whether the genetic alterations found in your cancer match genetic changes that are associated with known therapies that may have not been previously considered by your treating doctor. Performing genetic testing is a powerful diagnostic tool that may also give you clarification of your cancer type.
All clinically relevant genetic alterations and possible clinical trials will be reported in a clear and easy to read personalised XING Genomic Services report. The information surrounding your results will facilitate a discussion between you and your medical team.

Which test is right for you?

HRD Test

This is a multi-gene test that analyses 18 genes involved in homologous recombination repair deficiency (HRD) and 8 genes that are diagnostically significant. This test is aimed at breast, ovarian, prostate, and pancreatic cancers.

In addition, epigenetic causes of HRD can be interrogated by testing the BRCA1 and RAD51C gene promoters.

Genes covered include:
ATR, ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK2, RAD50, RAD51, RAD51C, RAD51D, FANCA, FANCC, FAND2, FANCE, FANCF, and MRE11A; hot spot regions of PALB2 and NBN; and other genes of diagnostic significance including ARID1A, BRAF, CNTTB1, KRAS, PIK3CA, PPP2RIA, PTEN, and TP53.

STP Test

This is a multi-gene test that analyses hotspot alterations considered to be driving mutations in solid tumours. It includes hotspots in 47 genes involved in colorectal, melanoma, thyroid, non-small cell lung, and pancreatic cancers, as well as gastro-intestinal stromal tumours (GIST) and gliomas.

Genes covered include:
AKT1, ALK, ARAF, BRAF, CDKN2A, CTNNB1, CYSLTR2, DDR2, EGFR, E1F1AX, ERBB2, ERBB4, FBXW7, FGFR1, FGFR2, FGFR3, GNA11, GNAQ, GNAS, H3F3A, HIST1H3B, HRAS, IDH1, IDH2, KIT, KRAS, MAP2K1, MET, NRAS, NTRK1, PDGFRA, PIK3CA, PLCB4, POLD1, POLE, PTEN, PTPN11, RAC1, RAF1, RET, SF3B1, SMAD4, SRSF2, STK11, TERT promoter, TP53, and TSHR. 

Checklist

NATA ISO 15189 accredited

XING Genomics Services delivers array-based and customised massively parallel sequencing solutions to clients in industry and academia using the iScan, NextSeq550, and NovaSeq platforms.

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